Monday, May 9, 2011

Diverticular disease of colon common in western society

WHERE REFINED DIETS ARE MORE COMMON THAN RICH IN FIBRE


DIVERTICULAR DISEASES OF COLON 

Diverticula of colon are acquired rupture of colonic mucosa ,protruding through broadside muscle at points where murder vessels understand colonic surround .They consist of mucosa and submucosa that have cut the muscular coats . They are pulsion diverticula being pushed out by increased intraluminal push .Although they haw involve the whole of the colon .They are most ordinary in the colon

Diverticular disease is most ordinary in Western society ,where civilised diets are more ordinary than diets rich in fibre and hence the stool is inferior bulky . Patients with diverticular disease have shortened ,thickened colonic muscle which reflects work hypertrophy from years of  a baritone fibre diet and resulting small hard stools .High intra-luminal pressure occur ,pushing the diverticulae out through the surround .The inclination of divertculae to form in the colon colon is explained by Laplace's law which states that the push within a tube is
inversely proportional to the radius.

PATHOGENESIS 

DIVERTICULOSIS two factors are essential 1.exaggerated peristaltic contractions with abnormal elevation of intraluminal push ,and foci of muscle imperfectness in colonic surround.

DIVERTICULITIS it is the secondary land and is cod to rousing of one or more diverticula.

MICROSCOPIC FEATURES


DIVERTICULOSIS 

Muscular hypertrophy in colonic segments affected by diverticular changes.saccule are found penetrating between the mesentric and lateral teniae at points where entering arterioles branch out into submucosa .Diverticulae are small ,flask like or spherical outpouchings usually 0.5 to 1 cm in diameyer .Walls of diverticula are usually thin ,made up of mucosa and submucosa enclosed within fat or an intact peritoneal covering .

DIVERTCULITIS 


Inflammatory changes are present ,to produce both diverticulitis and periverticulitis and sometimes localized peritonitis .


SIGN AND SYMPTOMS OF DIVERTICULOSIS AND DIVERTICULITIS

Most patients with diverticulosis have no symptoms. Many will never know they have the condition until it is discovered during an endoscopic or radiographic (Xray) examination. While most people have no symptoms, some individuals may experience pain or discomfort in the left lower abdomen, bloating, and/or a change in bowel habits.

Other conditions such as irritable bowel syndrome and stomach ulcers cause similar problems, so the symptoms do not always mean a person has diverticulosis. People with chronic symptoms should visit their doctor or health care provider.

The most common symptom of diverticulitis is abdominal pain. The most common sign on examination is tenderness in the lower left side of the abdomen. Usually, the pain is severe and comes on suddenly, but it can also be mild and become worse over several days. The intensity of the pain can fluctuate. A person may experience cramping, nausea, vomiting, fever, chills, or a change in bowel habits...... read more



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